USC/Mizzou Statistical Comparison
Scoring Defense - USC 6th , Mizzou 4th
Rushing Defense - USC 5th , Mizzou 3rd
Passing Defense - USC 3rd, Mizzou 12th
Total Defense - USC 3rd, Mizzou 7th
Sacks - USC 6th, Mizzou 1st
Scoring Offense - USC 8th, Mizzou 2nd
Rushing Offense - USC 3rd, Mizzou 2nd
Passing Offense - USC 8th, Mizzou 3rd
Total Offense - USC 5th, Mizzou 2nd
Penalties - USC 10th, Mizzou 3rd
Turnover margin - USC 12th, Mizzou 1st
So by looking at these, it appears like USC needs to take care of the football first and foremost. Mizzou has a ridiculous turnover margin.
It also appears like USC has a chance to put the ball in the air with success as long as they can keep the QB's jersey clean (this is where Ronald Patrick's return helps a ton).
Something has to give when it comes to USC's rush offense vs Mizzou's rush defense. Same with Mizzou's pass offense vs USC's pass defense.
Key to the game might be containing Mizzou's rush offense. But I'm guessing that a lot of that had to do with James Franklin running the football. Henry Josey is a dynamite running back though.